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Commander
Artifact
When Contagion Engine enters the battlefield, put a -1/-1 counter on each creature target player controls. {4}, {T}: Proliferate, then proliferate again. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)
Equipped creature gets +2/+2 and has protection from white and from blue. Whenever equipped creature deals combat damage to a player, put a +1/+1 counter on a creature you control, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.) Equip {2}
Creature
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.) Skrelv, Defector Mite can't block. {W/P}, {T}: Choose a color. Another target creature you control gains toxic 1 and hexproof from that color until end of turn. It can't be blocked by creatures of that color this turn. ({W/P} can be paid with either {W} or 2 life.)
Lifelink, toxic 1 Whenever you proliferate, choose one — • If you don't control a creature named The Hollow Sentinel, create The Hollow Sentinel, a legendary 3/3 colorless Phyrexian Golem artifact creature token. • Target artifact creature you control gains flying and lifelink until end of turn.