Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Lashwrithe

Living weapon (When this Equipment enters the battlefield, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +1/+1 for each Swamp you control.
Equip {B/P}{B/P} ({B/P} can be paid with either {B} or 2 life.)

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Kaervek, the Spiteful

Dread Presence

Whenever a Swamp enters the battlefield under your control, choose one —
• You draw a card and you lose 1 life.
• Dread Presence deals 2 damage to any target and you gain 2 life.

Blightsteel Colossus

Trample, infect, indestructible
If Blightsteel Colossus would be put into a graveyard from anywhere, reveal Blightsteel Colossus and shuffle it into its owner's library instead.

The Meathook Massacre

When The Meathook Massacre enters the battlefield, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Mikaeus, the Unhallowed

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
Whenever a Human deals damage to you, destroy it.
Other non-Human creatures you control get +1/+1 and have undying. (When a creature with undying dies, if it had no +1/+1 counters on it, return it to the battlefield under its owner's control with a +1/+1 counter on it.)

Mana Crypt

At the beginning of your upkeep, flip a coin. If you lose the flip, Mana Crypt deals 3 damage to you.
{T}: Add {C}{C}.

Gauntlet of Power

As Gauntlet of Power enters the battlefield, choose a color.
Creatures of the chosen color get +1/+1.
Whenever a basic land is tapped for mana of the chosen color, its controller adds an additional one mana of that color.

Crawlspace

No more than two creatures can attack you each combat.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Sword of Feast and Famine

Equipped creature gets +2/+2 and has protection from black and from green.
Whenever equipped creature deals combat damage to a player, that player discards a card and you untap all lands you control.
Equip {2}

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Shambling Ghast

When Shambling Ghast dies, choose one —
• Brave the Stench — Target creature an opponent controls gets -1/-1 until end of turn.
• Search the Body — Create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Thran Dynamo

Ob Nixilis of the Black Oath

+2: Each opponent loses 1 life. You gain life equal to the life lost this way.
−2: Create a 5/5 black Demon creature token with flying. You lose 2 life.
−8: You get an emblem with "{1}{B}, Sacrifice a creature: You gain X life and draw X cards, where X is the sacrificed creature's power."
Ob Nixilis of the Black Oath can be your commander.

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Bad Moon

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Damnation

Destroy all creatures. They can't be regenerated.

Karn, Silver Golem

Whenever Karn, Silver Golem blocks or becomes blocked, it gets -4/+4 until end of turn.
{1}: Target noncreature artifact becomes an artifact creature with power and toughness each equal to its mana value until end of turn.

Damnable Pact

Target player draws X cards and loses X life.

Sol Ring

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Butcher of Malakir

Flying
Whenever Butcher of Malakir or another creature you control dies, each opponent sacrifices a creature.

Snow-Covered Swamp

Ashnod's Altar

Pathrazer of Ulamog

Annihilator 3 (Whenever this creature attacks, defending player sacrifices three permanents.)
Pathrazer of Ulamog can't be blocked except by three or more creatures.

Puppeteer Clique

Flying
When Puppeteer Clique enters the battlefield, put target creature card from an opponent's graveyard onto the battlefield under your control. It gains haste. At the beginning of your next end step, exile it.
Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Phyrexian Altar

Sacrifice a creature: Add one mana of any color.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Altar of Dementia

Sacrifice a creature: Target player mills cards equal to the sacrificed creature's power.

Nirkana Revenant

Whenever you tap a Swamp for mana, add an additional {B}.
{B}: Nirkana Revenant gets +1/+1 until end of turn.

Griselbrand

Flying, lifelink
Pay 7 life: Draw seven cards.

Wurmcoil Engine

Deathtouch, lifelink
When Wurmcoil Engine dies, create a 3/3 colorless Phyrexian Wurm artifact creature token with deathtouch and a 3/3 colorless Phyrexian Wurm artifact creature token with lifelink.

Caged Sun

As Caged Sun enters the battlefield, choose a color.
Creatures you control of the chosen color get +1/+1.
Whenever a land's ability causes you to add one or more mana of the chosen color, add one additional mana of that color.

Ancient Craving

You draw three cards and you lose 3 life.

Quicksilver Amulet

{4}, {T}: You may put a creature card from your hand onto the battlefield.

Mycosynth Lattice

All permanents are artifacts in addition to their other types.
All cards that aren't on the battlefield, spells, and permanents are colorless.
Players may spend mana as though it were mana of any color.

Black Market

Whenever a creature dies, put a charge counter on Black Market.
At the beginning of your precombat main phase, add {B} for each charge counter on Black Market.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Paragon of Open Graves

Other black creatures you control get +1/+1.
{2}{B}, {T}: Another target black creature you control gains deathtouch until end of turn. (Any amount of damage it deals to a creature is enough to destroy it.)

Ob Nixilis's Cruelty

Target creature gets -5/-5 until end of turn. If that creature would die this turn, exile it instead.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Leyline of the Void

If Leyline of the Void is in your opening hand, you may begin the game with it on the battlefield.
If a card would be put into an opponent's graveyard from anywhere, exile it instead.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Platinum Angel

Flying
You can't lose the game and your opponents can't win the game.

Gilded Lotus

Festergloom

Nonblack creatures get -1/-1 until end of turn.

Font of Mythos

At the beginning of each player's draw step, that player draws two additional cards.

Zulaport Cutthroat

Whenever Zulaport Cutthroat or another creature you control dies, each opponent loses 1 life and you gain 1 life.

Helm of Awakening

Jet Medallion

Black spells you cast cost {1} less to cast.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Bojuka Bog

Bojuka Bog enters the battlefield tapped.
When Bojuka Bog enters the battlefield, exile target player's graveyard.
{T}: Add {B}.

Geth, Lord of the Vault

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
{X}{B}: Put target artifact or creature card with mana value X from an opponent's graveyard onto the battlefield under your control tapped. Then that player mills X cards.

Crucible of Worlds

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Abyssal Persecutor

Flying, trample
You can't win the game and your opponents can't lose the game.

Feldon's Cane

{T}, Exile Feldon's Cane: Shuffle your graveyard into your library.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Demonic Tutor

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent or discards a card.

Ivory Crane Netsuke

At the beginning of your upkeep, if you have seven or more cards in hand, you gain 4 life.

Demon's Horn

Whenever a player casts a black spell, you may gain 1 life.

Kaldra Compleat

Living weapon
Indestructible
Equipped creature gets +5/+5 and has first strike, trample, indestructible, haste, and "Whenever this creature deals combat damage to a creature, exile that creature."
Equip {7}