Near-Death Experience

At the beginning of your upkeep, if you have exactly 1 life, you win the game.

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Tainted Field

{T}: Add {C}.
{T}: Add {W} or {B}. Activate only if you control a Swamp.

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Deep Gnome Terramancer

Flash
Mold Earth — Whenever one or more lands enter the battlefield under an opponent's control without being played, you may search your library for a Plains card, put it onto the battlefield tapped, then shuffle. Do this only once each turn.

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter the battlefield tapped.

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Ormendahl, Profane Prince

Westvale Abbey

{T}: Add {C}.
{5}, {T}, Pay 1 life: Create a 1/1 white and black Human Cleric creature token.
{5}, {T}, Sacrifice five creatures: Transform Westvale Abbey, then untap it.

Westvale Abbey // Ormendahl, Profane Prince

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Grimclimb Pathway

Brightclimb Pathway

Brightclimb Pathway // Grimclimb Pathway

Sickening Dreams

As an additional cost to cast this spell, discard X cards.
Sickening Dreams deals X damage to each creature and each player.

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov of the Ghost Council.
{W}{B}, Remove six +1/+1 counters from Karlov of the Ghost Council: Exile target creature.

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Night's Whisper

Hour of Revelation

This spell costs {3} less to cast if there are ten or more nonland permanents on the battlefield.
Destroy all nonland permanents.

Koskun Falls

At the beginning of your upkeep, sacrifice Koskun Falls unless you tap an untapped creature you control.
Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Dark Ritual

Reprieve

Return target spell to its owner's hand.
Draw a card.

Have

Surge of Salvation

You and permanents you control gain hexproof until end of turn. Prevent all damage that black and/or red sources would deal to creatures you control this turn.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Crawlspace

No more than two creatures can attack you each combat.

The Book of Exalted Deeds

At the beginning of your end step, if you gained 3 or more life this turn, create a 3/3 white Angel creature token with flying.
{W}{W}{W}, {T}, Exile The Book of Exalted Deeds: Put an enlightened counter on target Angel. It gains "You can't lose the game and your opponents can't win the game." Activate only as a sorcery.

Glacial Chasm

Cumulative upkeep—Pay 2 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
When Glacial Chasm enters the battlefield, sacrifice a land.
Creatures you control can't attack.
Prevent all damage that would be dealt to you.

Vindicate

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Isolated Chapel

Isolated Chapel enters the battlefield tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Silent Clearing

{T}, Pay 1 life: Add {W} or {B}.
{1}, {T}, Sacrifice Silent Clearing: Draw a card.

Blacksmith's Skill

Target permanent gains hexproof and indestructible until end of turn. If it's an artifact creature, it gets +2/+2 until end of turn.

Blood Celebrant

{B}, Pay 1 life: Add one mana of any color.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Forbidden Orchard

{T}: Add one mana of any color.
Whenever you tap Forbidden Orchard for mana, target opponent creates a 1/1 colorless Spirit creature token.

Mutavault

{T}: Add {C}.
{1}: Mutavault becomes a 2/2 creature with all creature types until end of turn. It's still a land.

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Bojuka Bog

Bojuka Bog enters the battlefield tapped.
When Bojuka Bog enters the battlefield, exile target player's graveyard.
{T}: Add {B}.

Orzhov Signet

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Black Market Connections

At the beginning of your precombat main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Sol Ring

Pact Weapon

As long as Pact Weapon is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Swamp

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Windborn Muse

Flying
Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Oketra's Last Mercy

Your life total becomes equal to your starting life total. Lands you control don't untap during your next untap step.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put Sensei's Divining Top on top of its owner's library.

Snuff Out

If you control a Swamp, you may pay 4 life rather than pay this spell's mana cost.
Destroy target nonblack creature. It can't be regenerated.

Authority of the Consuls

Creatures your opponents control enter the battlefield tapped.
Whenever a creature enters the battlefield under an opponent's control, you gain 1 life.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Liesa, Shroud of Dusk

Rather than pay {2} for each previous time you've cast this spell from the command zone this game, pay 2 life that many times.
Flying, lifelink
Whenever a player casts a spell, they lose 2 life.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Greed

Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

City of Brass

Whenever City of Brass becomes tapped, it deals 1 damage to you.
{T}: Add one mana of any color.

Sunlit Marsh

({T}: Add {W} or {B}.)
Sunlit Marsh enters the battlefield tapped.

Solemnity

Players can't get counters.
Counters can't be put on artifacts, creatures, enchantments, or lands.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Nine Lives

Hexproof
If a source would deal damage to you, prevent that damage and put an incarnation counter on Nine Lives.
When there are nine or more incarnation counters on Nine Lives, exile it.
When Nine Lives leaves the battlefield, you lose the game.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Esper Sentinel

Whenever an opponent casts their first noncreature spell each turn, draw a card unless that player pays {X}, where X is Esper Sentinel's power.

Vault of Champions

Vault of Champions enters the battlefield tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Sign in Blood

Target player draws two cards and loses 2 life.

Delaying Shield

If damage would be dealt to you, put that many delay counters on Delaying Shield instead.
At the beginning of your upkeep, remove all delay counters from Delaying Shield. For each delay counter removed this way, you lose 1 life unless you pay {1}{W}.

Castle Locthwain

Castle Locthwain enters the battlefield tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Archivist of Oghma

Flash
Whenever an opponent searches their library, you gain 1 life and draw a card.

Skirge Familiar

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Snowfield Sinkhole

({T}: Add {W} or {B}.)
Snowfield Sinkhole enters the battlefield tapped.

Orzhov Basilica

Orzhov Basilica enters the battlefield tapped.
When Orzhov Basilica enters the battlefield, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Command Tower

Thalia, Heretic Cathar

First strike
Creatures and nonbasic lands your opponents control enter the battlefield tapped.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Pain's Reward

Each player may bid life. You start the bidding with a bid of any number. In turn order, each player may top the high bid. The bidding ends if the high bid stands. The high bidder loses life equal to the high bid and draws four cards.

Intervention Pact

The next time a source of your choice would deal damage to you this turn, prevent that damage. You gain life equal to the damage prevented this way.
At the beginning of your next upkeep, pay {1}{W}{W}. If you don't, you lose the game.

Plains

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Leechridden Swamp

({T}: Add {B}.)
Leechridden Swamp enters the battlefield tapped.
{B}, {T}: Each opponent loses 1 life. Activate only if you control two or more black permanents.

Hex Parasite

{X}{B/P}: Remove up to X counters from target permanent. For each counter removed this way, Hex Parasite gets +1/+0 until end of turn. ({B/P} can be paid with either {B} or 2 life.)

Defiler of Faith

Vigilance
As an additional cost to cast white permanent spells, you may pay 2 life. Those spells cost {W} less to cast if you paid life this way. This effect reduces only the amount of white mana you pay.
Whenever you cast a white permanent spell, create a 1/1 white Soldier creature token.