Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Elder Brain

Menace
Whenever Elder Brain attacks a player, exile all cards from that player's hand, then they draw that many cards. You may play lands and cast spells from among the exiled cards for as long as they remain exiled. If you cast a spell this way, you may spend mana as though it were mana of any color to cast it.

Blessing of Leeches

Flash
Enchant creature
At the beginning of your upkeep, you lose 1 life.
{0}: Regenerate enchanted creature.

Witch's Cottage

({T}: Add {B}.)
Witch's Cottage enters the battlefield tapped unless you control three or more other Swamps.
When Witch's Cottage enters the battlefield untapped, you may put target creature card from your graveyard on top of your library.

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis, the Hate-Twisted deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Howling Mine

At the beginning of each player's draw step, if Howling Mine is untapped, that player draws an additional card.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Sol Ring

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Swamp

Snuff Out

If you control a Swamp, you may pay 4 life rather than pay this spell's mana cost.
Destroy target nonblack creature. It can't be regenerated.

Font of Mythos

At the beginning of each player's draw step, that player draws two additional cards.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Ob Nixilis Reignited

+1: You draw a card and you lose 1 life.
−3: Destroy target creature.
−8: Target opponent gets an emblem with "Whenever a player draws a card, you lose 2 life."

Feign Death

Until end of turn, target creature gains "When this creature dies, return it to the battlefield tapped under its owner's control with a +1/+1 counter on it."

Rankle, Master of Pranks

Flying, haste
Whenever Rankle, Master of Pranks deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Sign in Blood

Target player draws two cards and loses 2 life.

Languish

All creatures get -4/-4 until end of turn.

Buried Ruin

{T}: Add {C}.
{2}, {T}, Sacrifice Buried Ruin: Return target artifact card from your graveyard to your hand.

Howling Golem

Whenever Howling Golem attacks or blocks, each player draws a card.

Thran Dynamo

Starscream, Seeker Leader

Living metal (As long as it's your turn, this Vehicle is also a creature.)
Flying, menace, haste
Whenever Starscream deals combat damage to a player, if there is no monarch, that player becomes the monarch.
Whenever you become the monarch, convert Starscream.

Starscream, Power Hungry

More Than Meets the Eye {2}{B} (You may cast this card converted for {2}{B}.)
Flying
Whenever you draw a card, if you're the monarch, target opponent loses 2 life.
Whenever one or more creatures deal combat damage to you, convert Starscream.

Starscream, Power Hungry // Starscream, Seeker Leader

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Painful Lesson

Prismatic Lens

{T}: Add {C}.
{1}, {T}: Add one mana of any color.

Fractured Powerstone

{T}: Add {C}.
{T}: Roll the planar die. Activate only as a sorcery.

Foreboding Fruit

Target player draws two cards and loses 2 life.
Adamant — If at least three black mana was spent to cast this spell, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")

Blood Money

Destroy all creatures. For each nontoken creature destroyed this way, you create a tapped Treasure token.

Bojuka Bog

Bojuka Bog enters the battlefield tapped.
When Bojuka Bog enters the battlefield, exile target player's graveyard.
{T}: Add {B}.

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Pain's Reward

Each player may bid life. You start the bidding with a bid of any number. In turn order, each player may top the high bid. The bidding ends if the high bid stands. The high bidder loses life equal to the high bid and draws four cards.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Infernal Grasp

Destroy target creature. You lose 2 life.

Baleful Mastery

You may pay {1}{B} rather than pay this spell's mana cost.
If the {1}{B} cost was paid, an opponent draws a card.
Exile target creature or planeswalker.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Fell Stinger

Deathtouch
Exploit (When this creature enters the battlefield, you may sacrifice a creature.)
When Fell Stinger exploits a creature, target player draws two cards and loses 2 life.

Everflowing Chalice

Multikicker {2} (You may pay an additional {2} any number of times as you cast this spell.)
Everflowing Chalice enters the battlefield with a charge counter on it for each time it was kicked.
{T}: Add {C} for each charge counter on Everflowing Chalice.

Liquimetal Torque

{T}: Add {C}.
{T}: Target nonland permanent becomes an artifact in addition to its other types until end of turn.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Ancient Tomb

{T}: Add {C}{C}. Ancient Tomb deals 2 damage to you.

Teferi's Puzzle Box

At the beginning of each player's draw step, that player puts the cards in their hand on the bottom of their library in any order, then draws that many cards.

Dark Ritual

Zenith Chronicler

Whenever a player casts their first multicolored spell each turn, each other player draws a card.

Mikokoro, Center of the Sea

{T}: Add {C}.
{2}, {T}: Each player draws a card.

Damnable Pact

Target player draws X cards and loses X life.

Malakir Mire

Malakir Mire enters the battlefield tapped.
{T}: Add {B}.

Malakir Rebirth

Choose target creature. You lose 2 life. Until end of turn, that creature gains "When this creature dies, return it to the battlefield tapped under its owner's control."

Malakir Rebirth // Malakir Mire

Epicure of Blood

Eldritch Pact

Target player draws X cards and loses X life, where X is the number of cards in their graveyard.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Master of the Feast

Flying
At the beginning of your upkeep, each opponent draws a card.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Memory Jar

{T}, Sacrifice Memory Jar: Each player exiles all cards from their hand face down and draws seven cards. At the beginning of the next end step, each player discards their hand and returns to their hand each card they exiled this way.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Night's Whisper

Coveted Jewel

When Coveted Jewel enters the battlefield, draw three cards.
{T}: Add three mana of any one color.
Whenever one or more creatures an opponent controls attack you and aren't blocked, that player draws three cards and gains control of Coveted Jewel. Untap it.

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Reliquary Tower

Horn of Greed

Whenever a player plays a land, that player draws a card.

Runed Servitor

When Runed Servitor dies, each player draws a card.

Undying Malice

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Star Compass

Star Compass enters the battlefield tapped.
{T}: Add one mana of any color that a basic land you control could produce.

Anvil of Bogardan

Players have no maximum hand size.
At the beginning of each player's draw step, that player draws an additional card, then discards a card.

Blood Pact

Temple Bell

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.