Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Bloodlord of Vaasgoth

Bloodthirst 3 (If an opponent was dealt damage this turn, this creature enters the battlefield with three +1/+1 counters on it.)
Flying
Whenever you cast a Vampire creature spell, it gains bloodthirst 3.

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Sign in Blood

Target player draws two cards and loses 2 life.

Dark Impostor

{4}{B}{B}: Exile target creature and put a +1/+1 counter on Dark Impostor.
Dark Impostor has all activated abilities of all creature cards exiled with it.

Patron of the Vein

Flying
When Patron of the Vein enters the battlefield, destroy target creature an opponent controls.
Whenever a creature an opponent controls dies, exile it and put a +1/+1 counter on each Vampire you control.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Blood Tribute

Kicker—Tap an untapped Vampire you control. (You may tap a Vampire you control in addition to any other costs as you cast this spell.)
Target opponent loses half their life, rounded up. If this spell was kicked, you gain life equal to the life lost this way.

Drana, Liberator of Malakir

Flying, first strike
Whenever Drana, Liberator of Malakir deals combat damage to a player, put a +1/+1 counter on each attacking creature you control.

Butcher of Malakir

Flying
Whenever Butcher of Malakir or another creature you control dies, each opponent sacrifices a creature.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Nirkana Revenant

Whenever you tap a Swamp for mana, add an additional {B}.
{B}: Nirkana Revenant gets +1/+1 until end of turn.

Anowon, the Ruin Sage

At the beginning of your upkeep, each player sacrifices a non-Vampire creature.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Don't Have

Ashes to Ashes

Exile two target nonartifact creatures. Ashes to Ashes deals 5 damage to you.

Damnation

Destroy all creatures. They can't be regenerated.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Bloodline Culling

Choose one —
• Target creature gets -5/-5 until end of turn.
• Creature tokens get -2/-2 until end of turn.

Path of Ancestry

Path of Ancestry enters the battlefield tapped.
{T}: Add one mana of any color in your commander's color identity. When that mana is spent to cast a creature spell that shares a creature type with your commander, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Cordial Vampire

Whenever Cordial Vampire or another creature dies, put a +1/+1 counter on each Vampire you control.

Sudden Spoiling

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Until end of turn, creatures target player controls lose all abilities and have base power and toughness 0/2.

No Mercy

Whenever a creature deals damage to you, destroy it.

Vampire Nighthawk

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Kaya's Ghostform

Enchant creature or planeswalker you control
When enchanted permanent dies or is put into exile, return that card to the battlefield under your control.

Bloodtracker

Flying
{B}, Pay 2 life: Put a +1/+1 counter on Bloodtracker.
When Bloodtracker leaves the battlefield, draw a card for each +1/+1 counter on it.

Vampire of the Dire Moon

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Drag to the Underworld

This spell costs {X} less to cast, where X is your devotion to black. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Destroy target creature.

Nighthawk Scavenger

Flying, deathtouch, lifelink
Nighthawk Scavenger's power is equal to 1 plus the number of card types among cards in your opponents' graveyards.

Tragic Slip

Target creature gets -1/-1 until end of turn.
Morbid — That creature gets -13/-13 until end of turn instead if a creature died this turn.

Black Market

Whenever a creature dies, put a charge counter on Black Market.
At the beginning of your precombat main phase, add {B} for each charge counter on Black Market.

Slaughter Pact

Destroy target nonblack creature.
At the beginning of your next upkeep, pay {2}{B}. If you don't, you lose the game.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Go for the Throat

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Consuming Vapors

Target player sacrifices a creature. You gain life equal to that creature's toughness.
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)

Malakir Bloodwitch

Flying, protection from white
When Malakir Bloodwitch enters the battlefield, each opponent loses life equal to the number of Vampires you control. You gain life equal to the life lost this way.

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Tendrils of Corruption

Tendrils of Corruption deals X damage to target creature and you gain X life, where X is the number of Swamps you control.

Greed

Knight of the Ebon Legion

{2}{B}: Knight of the Ebon Legion gets +3/+3 and gains deathtouch until end of turn.
At the beginning of your end step, if a player lost 4 or more life this turn, put a +1/+1 counter on Knight of the Ebon Legion. (Damage causes loss of life.)

Mortuary Mire

Mortuary Mire enters the battlefield tapped.
When Mortuary Mire enters the battlefield, you may put target creature card from your graveyard on top of your library.
{T}: Add {B}.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Lord of Lineage

Flying
Other Vampire creatures you control get +2/+2.
{T}: Create a 2/2 black Vampire creature token with flying.

Bloodline Keeper

Flying
{T}: Create a 2/2 black Vampire creature token with flying.
{B}: Transform Bloodline Keeper. Activate only if you control five or more Vampires.

Bloodline Keeper // Lord of Lineage

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Sorin Markov

+2: Sorin Markov deals 2 damage to any target and you gain 2 life.
−3: Target opponent's life total becomes 10.
−7: You control target player during that player's next turn.

Hero's Downfall

Gilded Lotus

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Thran Dynamo

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Gifted Aetherborn

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Swamp

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle Decree of Pain, all creatures get -2/-2 until end of turn.

Force of Despair

If it's not your turn, you may exile a black card from your hand rather than pay this spell's mana cost.
Destroy all creatures that entered the battlefield this turn.

Sol Ring

Soul Shatter

Each opponent sacrifices a creature or planeswalker with the highest mana value among creatures and planeswalkers they control.

Blood Seeker

Whenever a creature enters the battlefield under an opponent's control, you may have that player lose 1 life.