Malfegor

Flying
When Malfegor enters the battlefield, discard your hand. Each opponent sacrifices a creature for each card discarded this way.

Chainer, Nightmare Adept

Discard a card: You may cast a creature spell from your graveyard this turn. Activate only once each turn.
Whenever a nontoken creature enters the battlefield under your control, if you didn't cast it from your hand, it gains haste until your next turn.

Magus of the Wheel

{1}{R}, {T}, Sacrifice Magus of the Wheel: Each player discards their hand, then draws seven cards.

Big Game Hunter

When Big Game Hunter enters the battlefield, destroy target creature with power 4 or greater. It can't be regenerated.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Blood Scrivener

If you would draw a card while you have no cards in hand, instead you draw two cards and you lose 1 life.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Anje's Ravager

Anje's Ravager attacks each combat if able.
Whenever Anje's Ravager attacks, discard your hand, then draw three cards.
Madness {1}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Containment Construct

Whenever you discard a card, you may exile that card from your graveyard. If you do, you may play that card this turn.

Glint-Horn Buccaneer

Haste
Whenever you discard a card, Glint-Horn Buccaneer deals 1 damage to each opponent.
{1}{R}, Discard a card: Draw a card. Activate only if Glint-Horn Buccaneer is attacking.

Archfiend of Ifnir

Flying
Whenever you cycle or discard another card, put a -1/-1 counter on each creature your opponents control.
Cycling {2} ({2}, Discard this card: Draw a card.)

Surly Badgersaur

Whenever you discard a creature card, put a +1/+1 counter on Surly Badgersaur.
Whenever you discard a land card, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
Whenever you discard a noncreature, nonland card, Surly Badgersaur fights up to one target creature you don't control.

Rakdos Charm

Choose one —
• Exile target player's graveyard.
• Destroy target artifact.
• Each creature deals 1 damage to its controller.

Ghirapur Orrery

Each player may play an additional land on each of their turns.
At the beginning of each player's upkeep, if that player has no cards in hand, that player draws three cards.

Phyrexian Dragon Engine

Double strike
When Phyrexian Dragon Engine enters the battlefield from your graveyard, you may discard your hand. If you do, draw three cards.
Unearth {3}{R}{R}
(Melds with Mishra, Claimed by Gix.)

Blood for the Blood God!

This spell costs {1} less to cast for each creature that died this turn.
Discard your hand, then draw eight cards. Blood for the Blood God! deals 8 damage to each opponent. Exile Blood for the Blood God!

Bag of Holding

Whenever you discard a card, exile that card from your graveyard.
{2}, {T}: Draw a card, then discard a card.
{4}, {T}, Sacrifice Bag of Holding: Return all cards exiled with Bag of Holding to their owner's hand.

Sire of Insanity

At the beginning of each end step, each player discards their hand.

Terminate

Destroy target creature. It can't be regenerated.

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Vindictive Flamestoker

Whenever you cast a noncreature spell, put an oil counter on Vindictive Flamestoker.
{6}{R}, Sacrifice Vindictive Flamestoker: Discard your hand, then draw four cards. This ability costs {1} less to activate for each oil counter on Vindictive Flamestoker.

Faithless Looting

Draw two cards, then discard two cards.
Flashback {2}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Avaricious Dragon

Flying
At the beginning of your draw step, draw an additional card.
At the beginning of your end step, discard your hand.