Damnation

Destroy all creatures. They can't be regenerated.

Cruel Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Blood Pact

Target player draws two cards and loses 2 life.

Bad Deal

You draw two cards and each opponent discards two cards. Each player loses 2 life.

Crushing Disappointment

Each player loses 2 life. You draw two cards.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Call of the Ring

At the beginning of your upkeep, the Ring tempts you.
Whenever you choose a creature as your Ring-bearer, you may pay 2 life. If you do, draw a card.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Diabolic Tutor

Ancient Craving

You draw three cards and you lose 3 life.

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Vampiric Tutor

Blood on the Snow

Choose one —
• Destroy all creatures.
• Destroy all planeswalkers.
Then return a creature or planeswalker card with mana value X or less from your graveyard to the battlefield, where X is the amount of {S} spent to cast this spell. ({S} is mana from a snow source.)

Nevinyrral's Disk

Nevinyrral's Disk enters the battlefield tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature enters the battlefield under your control, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Castle Locthwain

Castle Locthwain enters the battlefield tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Bloodgift Demon

Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.

Black Market Connections

At the beginning of your precombat main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Nasty End

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards. If the sacrificed creature was legendary, draw three cards instead.