Extirpate

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Choose target card in a graveyard other than a basic land card. Search its owner's graveyard, hand, and library for all cards with the same name as that card and exile them. Then that player shuffles.

Gatekeeper of Malakir

Kicker {B} (You may pay an additional {B} as you cast this spell.)
When Gatekeeper of Malakir enters the battlefield, if it was kicked, target player sacrifices a creature.

Thoughtseize

Target player reveals their hand. You choose a nonland card from it. That player discards that card. You lose 2 life.

Ghost Quarter

{T}: Add {C}.
{T}, Sacrifice Ghost Quarter: Destroy target land. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.

Disfigure

Target creature gets -2/-2 until end of turn.

Victim of Night

Destroy target non-Vampire, non-Werewolf, non-Zombie creature.

Inquisition of Kozilek

Target player reveals their hand. You choose a nonland card from it with mana value 3 or less. That player discards that card.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Surgical Extraction

({B/P} can be paid with either {B} or 2 life.)
Choose target card in a graveyard other than a basic land card. Search its owner's graveyard, hand, and library for any number of cards with the same name as that card and exile them. Then that player shuffles.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Memoricide

Choose a nonland card name. Search target player's graveyard, hand, and library for any number of cards with that name and exile them. Then that player shuffles.

Bile Blight

Target creature and all other creatures with the same name as that creature get -3/-3 until end of turn.

Phyrexian Obliterator

Trample
Whenever a source deals damage to Phyrexian Obliterator, that source's controller sacrifices that many permanents.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Murderous Cut

Delve (Each card you exile from your graveyard while casting this spell pays for {1}.)
Destroy target creature.

Castle Locthwain

Castle Locthwain enters the battlefield tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Swamp

Sudden Spoiling

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Until end of turn, creatures target player controls lose all abilities and have base power and toughness 0/2.

Mutilate

All creatures get -1/-1 until end of turn for each Swamp you control.

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Doom Blade

Fatal Push

Destroy target creature if it has mana value 2 or less.
Revolt — Destroy that creature if it has mana value 4 or less instead if a permanent you controlled left the battlefield this turn.

Geth's Verdict

Target player sacrifices a creature and loses 1 life.

Relic of Progenitus

{T}: Target player exiles a card from their graveyard.
{1}, Exile Relic of Progenitus: Exile all graveyards. Draw a card.

Go for the Throat

Desecration Demon

Flying
At the beginning of each combat, any opponent may sacrifice a creature. If a player does, tap Desecration Demon and put a +1/+1 counter on it.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Contaminated Ground

Enchant land
Enchanted land is a Swamp.
Whenever enchanted land becomes tapped, its controller loses 2 life.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters the battlefield, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Ultimate Price

Vampire Nighthawk

Dismember

({B/P} can be paid with either {B} or 2 life.)
Target creature gets -5/-5 until end of turn.